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სათაური: პილორული ჰელიკობაქტერიის ეპიდემიოლოგიური, კლინიკური და ლაბორატორიული კვლევა საქართველოში
დონორი ორგანიზაცია : BTEP&ISTC
ბიუჯეტი: 300000
გრანტის ნომერი : BTEP (#96) ISTC (#1195)
კვლევის მიმართულება: 8 სამედიცინო მეცნიერებები
კვლევის ქვემიმართულება: 8-331 ეპიდემიოლოგია
საკვანძო სიტყვები: ჰელიკობაქტერია, ეპიდემიოლოგია
პროექტის აღწერა : During 2007–2008, we prospectively recruited 390 subjects with gastrointestinal symptoms referred to five tertiary care centers for diagnostic upper endoscopy. We administered a questionnaire on potential risk factors and tested patients using three diagnostic tests: gastric biopsies underwent histological evaluation and rapid urease test (CLO test), and an ELISA was used to detect IgG against H. pylori in serum. We defined a case as having two or more positive results from the three available tests. Univariate and multivariate logistic regression analyses were performed. Results: Overall, 217 (56%) patients met the study case definition. Subjects diagnosed with cancer had the highest rate of H. pylori infection (62%), followed by those with gastritis (55%), and ulcer (54%). Age >30 years (adjusted odds ratio (aOR 2.6, 95% confidence interval (CI) 1.6–4.3) and residing in the capital city (aOR 0.6, 95% CI 0.4–0.9) were significantly associated with infection. In this large cohort with gastrointestinal symptoms, only age >30 years and living in the capital were significant factors associated with infection. Lower SES, less education, and crowding did not confer an increased risk, in contrast to the findings of previous studies. Population-based studies are needed to identify potential routes and risk factors of H. pylori infection in ROG.
მიმდინარეობის წლები : 01/03/2005 - 28/02/2009
პროექტის ხელმძღვანელი : ლიდერი არ მოიძებნა
პროექტის მენეჯერი:
პროექტში მონაწილე (ები) : დიმიტრი კორძაია 01/03/2005 - 28/02/2009
რაიმე უზუსტობის შემთხვევაში გთხოვთ   შეატყობინოთ ადმინისტრატორს